Human CRTAP activation kit by CRISPRa

CAT#: GA107166

CRTAP CRISPRa kit - CRISPR gene activation of human cartilage associated protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRTAP
• Locus ID: 10491
• Kit Components:

  GA107166G1, CRTAP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107166G2, CRTAP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107166G3, CRTAP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006371
• Synonyms: CASP; LEPREL3; OI7; P3H5
• Summary: The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. [provided by RefSeq, Jul 2008]