Human SEMA6B activation kit by CRISPRa

CAT#: GA107175

SEMA6B CRISPRa kit - CRISPR gene activation of human semaphorin 6B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEMA6B
• Locus ID: 10501
• Kit Components:

  GA107175G1, SEMA6B gRNA vector 1 in pCas-Guide-CRISPRa

  GA107175G2, SEMA6B gRNA vector 2 in pCas-Guide-CRISPRa

  GA107175G3, SEMA6B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020241, NM_032108, NM_133327
• Synonyms: SEM-SEMA-Y; SEMA-VIB; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B; SEMAN; SEMAN, semaZ, SEMA-VIB, Sema VIb, SEM-SEMA-Y; semaphorin 6B; semaphorin VIB; semaphorin Z; semaZ
• Summary: This gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development. [provided by RefSeq, Jul 2008]