Human CIB1 activation kit by CRISPRa

CAT#: GA107185

CIB1 CRISPRa kit - CRISPR gene activation of human calcium and integrin binding 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CIB1
• Locus ID: 10519
• Kit Components:

  GA107185G1, CIB1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107185G2, CIB1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107185G3, CIB1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277764, NM_006384, NR_102427, NR_102428
• Synonyms: CIB; CIBP; KIP1; PRKDCIP; SIP2-28
• Summary: This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]