Human Deformed Epidermal Autoregulatory Factor 1 (DEAF1) activation kit by CRISPRa

CAT#: GA107188

DEAF1 CRISPRa kit - CRISPR gene activation of human DEAF1 transcription factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DEAF1
• Locus ID: 10522
• Kit Components:

  GA107188G1, DEAF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107188G2, DEAF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107188G3, DEAF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001293634, NM_021008, NM_001367390
• Synonyms: MRD24; NUDR; SPN; ZMYND5
• Summary: This gene encodes a zinc finger domain-containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]