Human P3H3 activation kit by CRISPRa

CAT#: GA107200

P3H3 CRISPRa kit - CRISPR gene activation of human prolyl 3-hydroxylase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: P3H3
• Locus ID: 10536
• Kit Components:

  GA107200G1, P3H3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107200G2, P3H3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107200G3, P3H3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014262
• Synonyms: GRCB; HSU47926; LEPREL2
• Summary: The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor. [provided by RefSeq, Aug 2013]