Human Ubiquitin D (UBD) activation kit by CRISPRa

CAT#: GA107201

UBD CRISPRa kit - CRISPR gene activation of human ubiquitin D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBD
• Locus ID: 10537
• Kit Components:

  GA107201G1, UBD gRNA vector 1 in pCas-Guide-CRISPRa

  GA107201G2, UBD gRNA vector 2 in pCas-Guide-CRISPRa

  GA107201G3, UBD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006398
• Synonyms: FAT10; GABBR1; UBD-3
• Summary: This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types. [provided by RefSeq, Aug 2017]