Human Peroxiredoxin 4 (PRDX4) activation kit by CRISPRa

CAT#: GA107209

PRDX4 CRISPRa kit - CRISPR gene activation of human peroxiredoxin 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRDX4
• Locus ID: 10549
• Kit Components:

  GA107209G1, PRDX4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107209G2, PRDX4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107209G3, PRDX4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006406
• Synonyms: AOE37-2; AOE372; HEL-S-97n; PRX-4
• Summary: The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]