Human ARFGEF2 activation kit by CRISPRa

CAT#: GA107224

ARFGEF2 CRISPRa kit - CRISPR gene activation of human ADP ribosylation factor guanine nucleotide exchange factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARFGEF2
• Locus ID: 10564
• Kit Components:

  GA107224G1, ARFGEF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107224G2, ARFGEF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107224G3, ARFGEF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006420
• Synonyms: BIG2; dJ1164I10.1; PVNH2
• Summary: ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]