Human TCP1 beta (CCT2) activation kit by CRISPRa

CAT#: GA107235

CCT2 CRISPRa kit - CRISPR gene activation of human chaperonin containing TCP1 subunit 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCT2
• Locus ID: 10576
• Kit Components:

  GA107235G1, CCT2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107235G2, CCT2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107235G3, CCT2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001198842, NM_006431
• Synonyms: 99D8.1; CCT-beta; CCTB; HEL-S-100n; PRO1633; TCP-1-beta
• Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]