Human TACC2 activation kit by CRISPRa

CAT#: GA107238

TACC2 CRISPRa kit - CRISPR gene activation of human transforming acidic coiled-coil containing protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TACC2
• Locus ID: 10579
• Kit Components:

  GA107238G1, TACC2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107238G2, TACC2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107238G3, TACC2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291876, NM_001291877, NM_001291878, NM_001291879, NM_006997, NM_206860, NM_206861, NM_206862
• Synonyms: AZU-1; ECTACC
• Summary: Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]