Human RCL (DNPH1) activation kit by CRISPRa

CAT#: GA107248

DNPH1 CRISPRa kit - CRISPR gene activation of human 2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNPH1
• Locus ID: 10591
• Kit Components:

  GA107248G1, DNPH1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107248G2, DNPH1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107248G3, DNPH1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006443, NM_199184
• Synonyms: C6orf108; dJ330M21.3; RCL
• Summary: This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008]