Human PRPF8 activation kit by CRISPRa

CAT#: GA107250

PRPF8 CRISPRa kit - CRISPR gene activation of human pre-mRNA processing factor 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRPF8
• Locus ID: 10594
• Kit Components:

  GA107250G1, PRPF8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107250G2, PRPF8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107250G3, PRPF8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006445
• Synonyms: HPRP8; PRP8; PRPC8; RP13; SNRNP220
• Summary: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]