Human PAIP1 activation kit by CRISPRa

CAT#: GA107258

PAIP1 CRISPRa kit - CRISPR gene activation of human poly(A) binding protein interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PAIP1
• Locus ID: 10605
• Kit Components:

  GA107258G1, PAIP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107258G2, PAIP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107258G3, PAIP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006451, NM_182789, NM_183323
• Synonyms: MGC12360
• Summary: The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]