Human ERLIN1 activation kit by CRISPRa
CAT#: GA107266
ERLIN1 CRISPRa kit - CRISPR gene activation of human ER lipid raft associated 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | ERLIN1 |
Locus ID | 10613 |
Kit Components | GA107266G1, ERLIN1 gRNA vector 1 in pCas-Guide-CRISPRa GA107266G2, ERLIN1 gRNA vector 2 in pCas-Guide-CRISPRa GA107266G3, ERLIN1 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001100626, NM_006459, NM_001347856, NM_001347857, NM_001347858, NM_001347859, NM_001347860, NM_001347861, NR_144755, NR_144756, NR_144757, NR_144758, NR_144759, NR_144760 |
Synonyms | C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62 |
Summary | The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN405137 | ERLIN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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