ERLIN1 Human Gene Knockout Kit (CRISPR)
CAT#: KN405137
ERLIN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN405137 is the updated version of KN205137.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | ERLIN1 |
Locus ID | 10613 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001100626, NM_006459, NM_001347856, NM_001347857, NM_001347858, NM_001347859, NM_001347860, NM_001347861, NR_144755, NR_144756, NR_144757, NR_144758, NR_144759, NR_144760 |
Synonyms | C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62 |
Summary | The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA107266 | ERLIN1 CRISPRa kit - CRISPR gene activation of human ER lipid raft associated 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.