Human ARID3B activation kit by CRISPRa

CAT#: GA107272

ARID3B CRISPRa kit - CRISPR gene activation of human AT-rich interaction domain 3B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARID3B
• Locus ID: 10620
• Kit Components:

  GA107272G1, ARID3B gRNA vector 1 in pCas-Guide-CRISPRa

  GA107272G2, ARID3B gRNA vector 2 in pCas-Guide-CRISPRa

  GA107272G3, ARID3B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001307939, NM_006465
• Synonyms: BDP; DRIL2
• Summary: This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]