Human IMP3 (IGF2BP3) activation kit by CRISPRa

CAT#: GA107293

IGF2BP3 CRISPRa kit - CRISPR gene activation of human insulin like growth factor 2 mRNA binding protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IGF2BP3
• Locus ID: 10643
• Kit Components:

  GA107293G1, IGF2BP3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107293G2, IGF2BP3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107293G3, IGF2BP3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006547
• Synonyms: CT98; IMP-3; IMP3; KOC; KOC1; VICKZ3
• Summary: The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]