Human Lipophilin B (SCGB1D2) activation kit by CRISPRa

CAT#: GA107296

SCGB1D2 CRISPRa kit - CRISPR gene activation of human secretoglobin family 1D member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCGB1D2
• Locus ID: 10647
• Kit Components:

  GA107296G1, SCGB1D2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107296G2, SCGB1D2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107296G3, SCGB1D2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006551
• Synonyms: LIPB; LPHB; LPNB
• Summary: The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008]