Human SPINT2 activation kit by CRISPRa

CAT#: GA107301

SPINT2 CRISPRa kit - CRISPR gene activation of human serine peptidase inhibitor, Kunitz type 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPINT2
• Locus ID: 10653
• Kit Components:

  GA107301G1, SPINT2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107301G2, SPINT2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107301G3, SPINT2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166103, NM_021102
• Synonyms: DIAR3; HAI-2; HAI2; Kop; PB
• Summary: This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]