Human CD226 activation kit by CRISPRa

CAT#: GA107313

CD226 CRISPRa kit - CRISPR gene activation of human CD226 molecule

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD226
• Locus ID: 10666
• Kit Components:

  GA107313G1, CD226 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107313G2, CD226 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107313G3, CD226 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303618, NM_001303619, NM_006566
• Synonyms: DNAM-1; DNAM1; PTA1; TLiSA1
• Summary: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]