Human DLL3 activation kit by CRISPRa

CAT#: GA107326

DLL3 CRISPRa kit - CRISPR gene activation of human delta like canonical Notch ligand 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLL3
• Locus ID: 10683
• Kit Components:

  GA107326G1, DLL3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107326G2, DLL3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107326G3, DLL3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016941, NM_203486
• Synonyms: SCDO1
• Summary: This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]