Human Fuc-TIX (FUT9) activation kit by CRISPRa

CAT#: GA107330

FUT9 CRISPRa kit - CRISPR gene activation of human fucosyltransferase 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FUT9
• Locus ID: 10690
• Kit Components:

  GA107330G1, FUT9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107330G2, FUT9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107330G3, FUT9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006581
• Synonyms: Fuc-TIX
• Summary: The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011]