Human NFAT5 activation kit by CRISPRa

CAT#: GA107348

NFAT5 CRISPRa kit - CRISPR gene activation of human nuclear factor of activated T cells 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NFAT5
• Locus ID: 10725
• Kit Components:

  GA107348G1, NFAT5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107348G2, NFAT5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107348G3, NFAT5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113178, NM_006599, NM_138713, NM_138714, NM_173214, NM_173215, NM_001367709
• Synonyms: NF-AT5; NFATL1; NFATZ; OREBP; TONEBP
• Summary: The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]