Human PLK4 activation kit by CRISPRa

CAT#: GA107353

PLK4 CRISPRa kit - CRISPR gene activation of human polo like kinase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLK4
• Locus ID: 10733
• Kit Components:

  GA107353G1, PLK4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107353G2, PLK4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107353G3, PLK4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190799, NM_001190801, NM_014264
• Synonyms: MCCRP2; SAK; STK18
• Summary: This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]