Human PLK2 activation kit by CRISPRa

CAT#: GA107379

PLK2 CRISPRa kit - CRISPR gene activation of human polo like kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLK2
• Locus ID: 10769
• Kit Components:

  GA107379G1, PLK2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107379G2, PLK2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107379G3, PLK2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252226, NM_006622, N66865
• Synonyms: hPlk2; hSNK; SNK
• Summary: The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]