Human NOXA1 activation kit by CRISPRa

CAT#: GA107411

NOXA1 CRISPRa kit - CRISPR gene activation of human NADPH oxidase activator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NOXA1
• Locus ID: 10811
• Kit Components:

  GA107411G1, NOXA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107411G2, NOXA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107411G3, NOXA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256067, NM_001256068, NM_006647
• Synonyms: NY-CO-31; p51NOX; SDCCAG31
• Summary: This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]