Human FTCD activation kit by CRISPRa

CAT#: GA107423

FTCD CRISPRa kit - CRISPR gene activation of human formimidoyltransferase cyclodeaminase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FTCD
• Locus ID: 10841
• Kit Components:

  GA107423G1, FTCD gRNA vector 1 in pCas-Guide-CRISPRa

  GA107423G2, FTCD gRNA vector 2 in pCas-Guide-CRISPRa

  GA107423G3, FTCD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320412, NM_006657, NM_206965
• Synonyms: LCHC1
• Summary: The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2009]