Human C7orf16 (PPP1R17) activation kit by CRISPRa

CAT#: GA107424

PPP1R17 CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory subunit 17

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R17
• Locus ID: 10842
• Kit Components:

  GA107424G1, PPP1R17 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107424G2, PPP1R17 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107424G3, PPP1R17 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145123, NM_006658
• Synonyms: C7orf16; GSBS
• Summary: The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]