Human CLPX activation kit by CRISPRa
CAT#: GA107426
CLPX CRISPRa kit - CRISPR gene activation of human caseinolytic mitochondrial matrix peptidase chaperone subunit
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | CLPX |
Locus ID | 10845 |
Kit Components | GA107426G1, CLPX gRNA vector 1 in pCas-Guide-CRISPRa GA107426G2, CLPX gRNA vector 2 in pCas-Guide-CRISPRa GA107426G3, CLPX gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_006660, NR_133680 |
Synonyms | ClpX caseinolytic peptidase X homolog (E. coli); ClpX caseinolytic protease X homolog; energy-dependent regulator of proteolysis |
Summary | The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN415555 | CLPX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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