Human RUVBL2 activation kit by CRISPRa

CAT#: GA107433

RUVBL2 CRISPRa kit - CRISPR gene activation of human RuvB like AAA ATPase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RUVBL2
• Locus ID: 10856
• Kit Components:

  GA107433G1, RUVBL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107433G2, RUVBL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107433G3, RUVBL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006666, NM_001321190, NM_001321191, NR_135578
• Synonyms: CGI-46; ECP51; INO80J; REPTIN; RVB2; TIH2; TIP48; TIP49B
• Summary: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008]