Human ADAM28 activation kit by CRISPRa

CAT#: GA107438

ADAM28 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 28

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADAM28
• Locus ID: 10863
• Kit Components:

  GA107438G1, ADAM28 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107438G2, ADAM28 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107438G3, ADAM28 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304351, NM_014265, NM_021777, NM_021778, NR_130709, NR_130710
• Synonyms: ADAM 28; eMDC II; eMDCII; MDC-L; MDCL
• Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]