Human NMU activation kit by CRISPRa

CAT#: GA107447

NMU CRISPRa kit - CRISPR gene activation of human neuromedin U

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NMU
• Locus ID: 10874
• Kit Components:

  GA107447G1, NMU gRNA vector 1 in pCas-Guide-CRISPRa

  GA107447G2, NMU gRNA vector 2 in pCas-Guide-CRISPRa

  GA107447G3, NMU gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001292045, NM_001292046, NM_006681, NR_120489
• Summary: This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015]