Human BLCAP activation kit by CRISPRa

CAT#: GA107474

BLCAP CRISPRa kit - CRISPR gene activation of human BLCAP apoptosis inducing factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BLCAP
• Locus ID: 10904
• Kit Components:

  GA107474G1, BLCAP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107474G2, BLCAP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107474G3, BLCAP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167820, NM_001167821, NM_001167822, NM_001167823, NM_001317074, NM_001317075, NM_006698
• Synonyms: BC10
• Summary: This gene encodes a protein that reduces cell growth by stimulating apoptosis. Alternative splicing and the use of alternative promoters result in multiple transcript variants encoding the same protein. This gene is imprinted in brain where different transcript variants are expressed from each parental allele. Transcript variants initiating from the upstream promoter are expressed preferentially from the maternal allele, while transcript variants initiating downstream of the interspersed NNAT gene (GeneID:4826) are expressed from the paternal allele. Transcripts at this locus may also undergo A to I editing, resulting in amino acid changes at three positions in the N-terminus of the protein. [provided by RefSeq, Nov 2015]