Human Urotensin II (UTS2) activation kit by CRISPRa

CAT#: GA107480

UTS2 CRISPRa kit - CRISPR gene activation of human urotensin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UTS2
• Locus ID: 10911
• Kit Components:

  GA107480G1, UTS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107480G2, UTS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107480G3, UTS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006786, NM_021995
• Synonyms: PRO1068; U-II; UCN2; UII
• Summary: This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]