Human RALBP1 activation kit by CRISPRa

CAT#: GA107495

RALBP1 CRISPRa kit - CRISPR gene activation of human ralA binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RALBP1
• Locus ID: 10928
• Kit Components:

  GA107495G1, RALBP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107495G2, RALBP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107495G3, RALBP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006788
• Synonyms: RIP1; RLIP1; RLIP76
• Summary: RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]). [supplied by OMIM, Nov 2010]