Human POP1 activation kit by CRISPRa

CAT#: GA107503

POP1 CRISPRa kit - CRISPR gene activation of human POP1 homolog, ribonuclease P/MRP subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POP1
• Locus ID: 10940
• Kit Components:

  GA107503G1, POP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107503G2, POP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107503G3, POP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145860, NM_001145861, NM_015029
• Synonyms: KIAA0061; MGC17365
• Summary: This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]