Human MSL3L1 (MSL3) activation kit by CRISPRa

CAT#: GA107506

MSL3 CRISPRa kit - CRISPR gene activation of human MSL complex subunit 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MSL3
• Locus ID: 10943
• Kit Components:

  GA107506G1, MSL3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107506G2, MSL3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107506G3, MSL3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001193270, NM_001282174, NM_006800, NM_078628, NM_078629, NM_078630
• Synonyms: MSL3L1
• Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]