Human ERP29 activation kit by CRISPRa

CAT#: GA107523

ERP29 CRISPRa kit - CRISPR gene activation of human endoplasmic reticulum protein 29

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ERP29
• Locus ID: 10961
• Kit Components:

  GA107523G1, ERP29 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107523G2, ERP29 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107523G3, ERP29 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001034025, NM_006817
• Synonyms: C12orf8; ERp28; ERp31; HEL-S-107; PDI-DB; PDIA9
• Summary: This gene encodes a protein which localizes to the lumen of the endoplasmic reticulum (ER). It is a member of the protein disulfide isomerase (PDI) protein family but lacks an active thioredoxin motif, suggesting that this protein does not function as a disulfide isomerase. The canonical protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]