Human TLK2 activation kit by CRISPRa

CAT#: GA107561

TLK2 CRISPRa kit - CRISPR gene activation of human tousled like kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TLK2
• Locus ID: 11011
• Kit Components:

  GA107561G1, TLK2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107561G2, TLK2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107561G3, TLK2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001112707, NM_001284333, NM_001284363, NM_006852, NM_001330418
• Synonyms: HsHPK; PKU-ALPHA
• Summary: This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]