Human LILRA3 activation kit by CRISPRa

CAT#: GA107576

LILRA3 CRISPRa kit - CRISPR gene activation of human leukocyte immunoglobulin like receptor A3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LILRA3
• Locus ID: 11026
• Kit Components:

  GA107576G1, LILRA3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107576G2, LILRA3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107576G3, LILRA3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001172654, NM_006865
• Synonyms: CD85E; HM31; HM43; ILT-6; ILT6; LIR-4; LIR4
• Summary: This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]