Human ESM1 activation kit by CRISPRa

CAT#: GA107620

ESM1 CRISPRa kit - CRISPR gene activation of human endothelial cell specific molecule 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ESM1
• Locus ID: 11082
• Kit Components:

  GA107620G1, ESM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107620G2, ESM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107620G3, ESM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135604, NM_007036
• Synonyms: endocan
• Summary: This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]