Human CDC37 activation kit by CRISPRa

CAT#: GA107663

CDC37 CRISPRa kit - CRISPR gene activation of human cell division cycle 37

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDC37
• Locus ID: 11140
• Kit Components:

  GA107663G1, CDC37 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107663G2, CDC37 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107663G3, CDC37 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007065
• Synonyms: P50CDC37
• Summary: The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]