Human PTP4A3 activation kit by CRISPRa

CAT#: GA107678

PTP4A3 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase 4A3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTP4A3
• Locus ID: 11156
• Kit Components:

  GA107678G1, PTP4A3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107678G2, PTP4A3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107678G3, PTP4A3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007079, NM_032611
• Synonyms: PRL-3; PRL-R; PRL3
• Summary: This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]