Human NUDT4 activation kit by CRISPRa

CAT#: GA107685

NUDT4 CRISPRa kit - CRISPR gene activation of human nudix hydrolase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NUDT4
• Locus ID: 11163
• Kit Components:

  GA107685G1, NUDT4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107685G2, NUDT4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107685G3, NUDT4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301022, NM_001301023, NM_001301024, NM_019094, NM_199040
• Synonyms: DIPP2; DIPP2alpha; DIPP2beta; HDCMB47P
• Summary: The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing. [provided by RefSeq, Jul 2008]