Human Plakophilin 3 (PKP3) activation kit by CRISPRa

CAT#: GA107708

PKP3 CRISPRa kit - CRISPR gene activation of human plakophilin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PKP3
• Locus ID: 11187
• Kit Components:

  GA107708G1, PKP3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107708G2, PKP3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107708G3, PKP3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303029, NM_007183
• Summary: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]