Human CEP250 activation kit by CRISPRa

CAT#: GA107711

CEP250 CRISPRa kit - CRISPR gene activation of human centrosomal protein 250

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEP250
• Locus ID: 11190
• Kit Components:

  GA107711G1, CEP250 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107711G2, CEP250 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107711G3, CEP250 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001035518, NM_001318219, NM_007186
• Synonyms: C-NAP1; centrosomal Nek2-associated protein 1; centrosomal protein, 250-KD; centrosomal protein 2; centrosomal protein 250kDa; centrosome associated protein; CEP2; CNAP1; MGC88542; OTTHUMP00000030757
• Summary: This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]