Human WIF1 activation kit by CRISPRa

CAT#: GA107715

WIF1 CRISPRa kit - CRISPR gene activation of human WNT inhibitory factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WIF1
• Locus ID: 11197
• Kit Components:

  GA107715G1, WIF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107715G2, WIF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107715G3, WIF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007191
• Synonyms: WIF-1
• Summary: The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]