Human DNA Polymerase iota (POLI) activation kit by CRISPRa
CAT#: GA107719
POLI CRISPRa kit - CRISPR gene activation of human DNA polymerase iota
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | POLI |
Locus ID | 11201 |
Kit Components | GA107719G1, POLI gRNA vector 1 in pCas-Guide-CRISPRa GA107719G2, POLI gRNA vector 2 in pCas-Guide-CRISPRa GA107719G3, POLI gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_007195, NM_001351610, NM_001351611, NM_001351612, NM_001351613, NM_001351614, NM_001351615, NM_001351616, NM_001351617, NM_001351618, NM_001351619, NM_001351620, NM_001351621, NM_001351632, NR_147257 |
Synonyms | RAD3OB; RAD30B |
Summary | The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN407550 | POLI - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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