Human PLPBP activation kit by CRISPRa

CAT#: GA107722

PLPBP CRISPRa kit - CRISPR gene activation of human pyridoxal phosphate binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLPBP
• Locus ID: 11212
• Kit Components:

  GA107722G1, PLPBP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107722G2, PLPBP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107722G3, PLPBP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007198, NM_001349346, NM_001349347, NM_001349348, NM_001349349
• Synonyms: FLJ11861
• Summary: This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017]