Human HPS5 activation kit by CRISPRa

CAT#: GA107739

HPS5 CRISPRa kit - CRISPR gene activation of human HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HPS5
• Locus ID: 11234
• Kit Components:

  GA107739G1, HPS5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107739G2, HPS5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107739G3, HPS5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007216, NM_181507, NM_181508
• Synonyms: AIBP63
• Summary: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]